产品货号:
Z10284
中文名称:
AANAT抗体
英文名称:
Anti-AANAT Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-AANAT Antibody |
指标别名 | AA NAT;AANAT;Serotonin acetylase;Serotonin N acetyltransferase;SNAT |
克隆性 | Polyclonal |
检验物种 | mouse |
应用范围 | WB,ELISA |
基因名称 | Aanat |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived mouse Aanat recombinant protein (Position:C24-C205). |
实际分子量 | 23KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Aralkylamine N-acetyltransferase (AANAT) (EC 2.3.1.87),also known as arylalkylamine N-acetyltransferase or serotonin N-acetyltransferase (SNAT),is an enzyme that is involved in the day/night rhythmic production of melatonin,by modification of serotonin.It is in humans encoded by the~2.5kb AANAT gene containing four exons,located on chromosome 17q25.The protein encoded by this gene belongs to the acetyltransferase superfamily.It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland.Melatonin is essential for the function of the circadian clock that influences activity and sleep.This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation.This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.Alternative splicing results in multiple transcript variants. |
Uniprot ID | O88816 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | arylalkylamine N-acetyltransferase |
蛋白名全称 | Serotonin N-acetyltransferase |
推荐稀释比 | Western blot(WB) 1:500~2000 (ELISA): 1:100~1000 |
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